GHR (ab 78426) and caspase 8 (ab 25901) antibodies was purchased from Abcam (Cambridge, MA, USA). β-Actin was procured from Sigma-Aldrich Corporation. Appropriate secondary antibodies were ...

Figure 2: Tyr phosphorylation of JAK2 and GHR and STAT5b activation are normal ... Cells were processed for immunoprecipitation using an anti-ERK1/2 antibody (2 μg, Upstate Biotech cat.

a growth hormone receptor (GHR) antagonist for the treatment of acromegaly; Phase 1 study expected to initiate in Second Half 2025 Marea to present at 43rd Annual J.P. Morgan Healthcare Conference ...