CIB1 is a 22-kDa regulatory protein previously implicated in cell survival and proliferation. However, the mechanism by which CIB1 regulates these processes is poorly defined. Here, we report that ...

In ovarian cancer metastases, a strong coexpression of CSF-1 and its receptor was associated with poor prognosis, 96 and GAPDH has recently been shown to bind and stabilize CSF-1 mRNA in this cell ...

How do cancer cells cope with an oxidation-resistant GAPDH? GAPDH-mutated cancer cells transplanted to mice grew into tumors significantly slower than cancer cells with normal GAPDH.

A multinational team of researchers, co-led by the Garvan Institute of Medical Research, has developed and tested a new AI ...

For roughly 400 years, microscopes have allowed us to observe increasingly smaller details. Today's most advanced instruments ...

These circulating tumor cells (CTCs) can join together into small clusters of up to a dozen cells and settle in other organs. There, the clusters grow into larger tumors, known as metastases.

Immune and tumor cell 'tug-of-war' controls anti-cancer activity Date: July 5, 2023 Source: St. Jude Children's Research Hospital Summary: Scientists have found that altering amounts of the ...

This enables the T cells to attack tumor cells in a targeted manner without damaging normal cells. PRAME is produced by many tumors, such as melanoma, ovarian cancer, sarcomas, and lung cancer.