Researchers have uncovered the mechanism underlying frontotemporal lobar degeneration (FTLD) caused by variants in the valosin-containing protein (VCP) gene. Their study, which used a fruit fly model, ...

Historically, frontotemporal lobar degeneration (FTLD), corticobasal degeneration (CBD) and progressive supranuclear palsy (PSP) were classified on the basis of distinct clinical and pathological ...

On the surface, the movement disorder amyotrophic lateral sclerosis (ALS), also known as Lou Gehrig's disease, and the cognitive disorder frontotemporal lobar degeneration (FTLD), which underlies ...

The classification of frontotemporal lobar dementias ... that include prominent apraxia (corticobasal degeneration), parkinsonism (frontotemporal lobar degeneration with MAPT (microtubule ...

New guidelines will help doctors identify patients with a common memory-loss syndrome that is often misdiagnosed as Alzheimer’s disease in older adults. The diagnostic criteria for limbic-predominant ...

ALLFTD: the ARTFL-LEFFTDS Longitudinal Frontotemporal Lobar Degeneration multisite research consortium. The ALLFTD consortium is an integrated group of academic medical centers partnered with patient ...

Neumann et al. have identified the ubiquitinated protein that forms inclusion bodies in neurons of both individuals with frontotemporal lobar degeneration (FTLD) and those with amyotrophic lateral ...

frontotemporal lobar dementia and Alzheimer's disease. A University of California, Irvine-led research team has discovered intricate molecular mechanisms driving the RNA processing defects that ...

and signs characteristic of frontotemporal lobar degeneration. Neurological skill resides in the ability to elicit symptoms and assess the validity of signs that confirm neurodegenerative and ...