“I was always interested in how cells decide their fate,” Zernicka-Goetz said. In the mouse developing embryo, she previously demonstrated a bias at the two-cell stage: one cell contributed more to ...

Unlike organoids, which model parts of single organs, the duo coaxed aggregates of mouse embryonic stem cells to carry out fundamental processes of development to become embryo-like entities, or ...

To work out which nutrients were important to induce diapause, the researchers grew early-stage mouse embryos in dishes ... include approaches such as embryo freezing. "We think our study can ...