Filamin is a homodimeric actin-binding protein that crosslinks and stabilizes cortical F-actin filaments and links them to plasma membranes by binding to transmembrane receptors or ion channels ...

On the basis of these studies, together with additional genome sequencing analysis of 92 subjects with HCM, we suggest that mutations in the FLNC gene encoding the sarcomeric protein filamin C are ...

New research published in Nature Communications has found that a protein called Filamin A is responsible for guiding receptors to their correct places in brain cells. These receptors control brain ...

Researchers led by Masahisa Katsuno, of Nagoya University Graduate School of Medicine in Japan, spotted filamin-A mingling with tau aggregates in the brains of people who had died with the disease.

Cassava is taking a different approach than other Alzheimer’s therapies by trying to stabilize a scaffolding protein called filamin A rather than clear amyloid plaques from the brain.