Fibroblastic reticular cells (FRCs) are heterogeneous stromal cells. Subsets of FRCs include: T cell zone reticular cells that produce interleukin-7 (IL-7) to support naive T cells; resident and ...

Their study reveals that specific cells, known as fibroblastic reticular cells (FRCs), create environments within tumors that help protect and activate immune cells to fight the cancer effectively.