FSH α-chains and β-chains are in green and cyan, respectively. FSHR HB is in red. The observed N-linked carbohydrates at N52 and N78 of FSH-α, N7 and N24 of FSH-β, ...

Unlike many GPCR ligands, FSH is a highly complex molecule, and it has been studied exhaustively 5.It is composed of two different subunits, α and β, each of which is decorated with two long ...

Zhu, LL, Blair, H, Cao, J, et al. Blocking antibody to the β-subunit of FSH prevents bone loss by inhibiting bone resorption and stimulating bone synthesis. Proc Natl Acad Sci U S A 2012;109: ...