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A landmark review in Nature Reviews Genetics dissects the rare and common genetic variants that shape human height. The paper ...
Johnson & Johnson’s Balversa was found to extend the lives of urothelial cancer patients with a genetic alteration ...
The recommendation was based on results from the Phase III THOR trial, which compared Balversa to chemotherapy.
The oral drug – Johnson & Johnson's Balversa (erdafitinib) – will become an option for adults with metastatic or unresectable ...
Overexpression of fibroblast growth factor receptor 3 (FGFR3) has been shown to drive oncogenesis in a subset of patients with multiple myeloma. However, epithelial cancers — such as bladder ...
Achondroplasia risk factors Achondroplasia is caused by a spontaneous mutation in a specific gene called FGFR3. About 98% of cases result from the exact same change in the DNA in this gene.