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A laboratory on Long Island has found a breakthrough in the fight against pancreatic cancer that can “intercept” its spread.
In a recent study, precancerous pancreatic lesions and some pancreatic ductal adenocarcinoma (PDAC) tumors harboring KRAS ...
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News-Medical.Net on MSNFGFR2 identified as key driver in KRAS-mutated pancreatic cancer progressionPrecancerous pancreatic lesions and some pancreatic ductal adenocarcinoma (PDAC) tumors harboring KRAS mutations had ...
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News-Medical.Net on MSNMouse and organoid models reveal FGFR2's role in pancreatic cancer aggression and interceptionPancreatic cancer is projected to become the second-deadliest cancer by 2030. By the time it's diagnosed, it's often ...
Results showed that FGFR2 gene deletion led to significantly fewer precancerous lesions and delayed PDAC tumor formation ...
“Fgfr2 is a gene found in all mammals that is important for embryonic development and organogenesis,” geneticist Kelly McGowan, a co-author of the study, said in a press release in 2024.
Scientists have found a way to 'intercept' pancreatic cancer. By inhibiting the cancer gene FGFR2, they were able to slow tumor formation. By targeting the FGFR2 and EGFR proteins, they were able to ...
Their goal was to stop the pancreatic tissue from becoming cancerous. Because FGFR2 is a known oncogene in other cancers, several inhibitors are already used in the clinic today. When Tonelli and ...
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