We further grouped fibrosis stages as F0-F1 (minimal fibrosis), F2-F3 (advanced fibrosis), F4 (cirrhosis) and F2-F4 (significant fibrosis). RNA was extracted from 140 μl serum samples using ...

Activity (necroinflammation) and fibrosis are two major histologic features of chronic hepatitis C included in different proposed classifications. One of the few validated scoring systems is ...

32.7% (p=0.004 vs placebo) of F3-F4 patients treated with 600 mg icosabutate achieved ≥1-stage improvement in fibrosis without worsening of MASH versus 9.6% of placebo treated patients as ...