Actin can be found in two forms, monomeric (G-actin) and filamentous (F-actin). The latter forms filaments that are essential for maintaining cell structure and many other functions.

Traditional phalloidin conjugates can have weakened affinity due to dye modification, leading to loss of signal over time after staining. In contrast, ActinBrite™ conjugates maintain strong F-actin ...

F-actin in young (left) and old (middle) fruit fly brains. When the Fsoh gene is knocked out, F-actin returns to a youthful state (right). Nature Communications/Edward Schmid ...

Forces generated by the actin cytoskeleton are highly dependent on the structural properties of molecular motors called myosin.

ActinBrite™ conjugates are ideal for imaging F-actin in fixed cells and tissues across a range of applications, including cytoskeletal studies, cell morphology analysis, and multiplex fluorescence ...

Shot can act as a molecular linker between microtubules and actin during dendrite pruning, suggesting an intriguing role in non-centrosomal microtubule organization. However, the experimental evidence ...