Although estradiol in this compound is more potent and believed to offer the most benefit for menopausal symptoms, 2 mg of estriol alone administered vaginally has beneficial effects on urogenital ...

[21] Estriol, a lower-potency estrogen ... 12 weeks with either isoflavone vaginal gel 4% (1 g/day), CEE cream (0.3 mg/day) or placebo gel. Women treated with isoflavone gel showed a similar ...