Examination revealed an intense erythema symmetrically distributed over her face, with a particularly marked involvement of the forehead, nose, cheeks, and chin and an evident sparing around the ...

In this double-blind trial, researchers randomized 180 patients (minimum age, 16) with annular skin lesions (erythema migrans) of ≥5 cm in diameter to 1 of 3 treatments: a single 2-g dose of ...