EphA2 on urinary extracellular vesicles as a novel diagnostic marker for bladder cancer and its effect on the invasiveness of bladder cancer. Authors: Eisuke Tomiyama, Kazutoshi Fujita, Taigo Kato, ...

Intoh, A., et al. (2024). EPHA2 is a novel cell surface marker of OCT4-positive undifferentiated cells during the differentiation of mouse and human pluripotent stem cells.

Researchers at MetroHealth and Case Western Reserve University have uncovered a mystery explaining how and why a protein receptor can suppress cancer or make it spread and grow. They determined that ...

Ephrin type-A receptor 2 (EphA2) is a type I transmembrane glycoprotein highly expressed in a wide range of tumors such as bladder, pancreatic, esophageal, colorectal, or non-small-cell lung cancer, ...

This study focuses on the EphA2 protein, traditionally associated with cancer, which researchers have now identified as essential for maintaining the lens’s clarity and function as it ages.

Nat Cell Biol. 2001 3:527-30. doi: 10.1038/35074604. PubMed PMID: 11331884. Miao H, Burnett E, Kinch M, Simon E, Wang B. Activation of EphA2 kinase suppresses integrin function and causes ...