The reaction of enol (ate)s with electrophiles is used extensively in organic synthesis for stereoselective C–C bond formation. Protein-based catalysts have had comparatively limited application ...

Nucleophilic addition of enolate anion to the carbonyl group (R = H, alkyl, phenyl) In the next step ß-hydroxy aldehyde or ketone is formed by reaction with water, and the reaction is completed by ...