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In Panel A, EBV nuclear antigen (EBNA) 2 up-regulates the expression of latent membrane proteins 1 and 2 (LMP-1 and LMP-2, respectively). EBNA-3 is a set of three proteins: EBNA-3A, EBNA-3B ...
When a cell that is carrying the virus undergoes division, it expresses EBV nuclear antigen 1 (EBNA-1) alone to allow the viral genome to divide along with the cell. In response to unknown signals ...
EBV EBNA 2 stimulates CDK9-dependent transcription and RNA polymerase II phosphorylation on serine 5
The DNA tumour virus Epstein–Barr virus (EBV) was the first virus to be isolated from a tumour biopsy sample and to be implicated in the development of human cancer. EBV has potent transforming ...
EBV nuclear antigen (EBNA). This tests for antibodies to EBNA. These antibodies will be seen if you've been infected by EBV for more than two to four months. You may continue to test positive for ...
A subset of latent EBV antigens is required for mediating immortalization of primary B-lymphocytes. Here we demonstrate that the carboxy-terminal region of the essential latent antigen ...
But up to 20% of people have antibodies to EA for years. EBV nuclear antigen (EBNA). You develop antibodies to EBNA 2 to 4 months after infection, and they last for the rest of your life.
EBNA-3C interaction with cyclin D1 also results ... and coimmunoprecipitation using both ectopically expressed as well as EBV-transformed cells Enhances MDM2 stabilization through blocking its ...
These elevated EBNA-specific antibody responses and corresponding T and B cell responses suggest a potential link between EBV infection and MS pathogenesis, underlining the need for further ...
and Elecsys EBV EBNA IgG, that detect antibodies specific to the Epstein-Barr virus (EBV), at different stages of infection. When used in combination, the three tests can help to define how far ...
To answer this, scientists measured the cellular response of MS patients to EBNA-1, a part of the EBV that can mimic the myelin coating of nerves which are the principal site of attack of the ...
Latent antigens Associated functions Linked with other human cancers Ref. EBNA-1 Assists in EBV episome maintenance and replication, blocks interaction between HAUSP and p53 to facilitate p53 ...
and Elecsys EBV EBNA IgG, that detect antibodies specific to the Epstein-Barr virus (EBV), at different stages of infection. When used in combination, the three tests can help to define how far ...
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