A single dominant EBV strain was found in all cases. EBNA-1 sequences were remarkably homogeneous, showing either a P-ala (2/12) or P-ala variant (9/12) sequence. Other EBNA-1 subtypes known to be ...

Latent antigens Associated functions Linked with other human cancers Ref. EBNA-1 Assists in EBV episome maintenance and replication, blocks interaction between HAUSP and p53 to facilitate p53 ...

Results From the PRODIGE 4/ACCORD 11 Randomized Trial We report on the use of adoptive transfer of EBNA-1–specific T cells in 10 pediatric and adult patients with EBV viremia and/or PTLD after SCT. No ...

In Panel A, EBV nuclear antigen (EBNA) 2 up-regulates the expression of latent membrane proteins 1 and 2 (LMP-1 and LMP-2, respectively). EBNA-3 is a set of three proteins: EBNA-3A, EBNA-3B ...

When a cell that is carrying the virus undergoes division, it expresses EBV nuclear antigen 1 (EBNA-1) alone to allow the viral genome to divide along with the cell. In response to unknown signals ...

type I (Burkitt's lymphoma), in which only the EBV-encoded nuclear antigen (EBNA-1) is expressed; type II (nasopharyngeal carcinoma), in which EBNA-1 is coexpressed along with the latent membrane ...

Subscribe for FREE To answer this, scientists measured the cellular response of MS patients to EBNA-1, a part of the EBV that can mimic the myelin coating of nerves which are the principal site of ...

To answer this, scientists measured the cellular response of MS patients to EBNA-1, a part of the EBV that can mimic the myelin coating of nerves which are the principal site of attack of the ...

EBV nuclear antigen (EBNA). This tests for antibodies to EBNA. These antibodies will be seen if you've been infected by EBV for more than two to four months. You may continue to test positive for ...

Since some of the patients received repetitive infusions and some received none (sufficient disease control was reached by conventional therapy), a total of 10 patients received EBV-specific T cells, ...