When an ECB female of the Z-race is ready to mate, she releases the E and Z isomers in a ratio of 3:97, and only Z-race males are attracted. E-females emit the same isomers but in a ratio of 98:2, and ...

Doxepin stands out as a notable example of a drug that is commercialized as a mixture of two geometric isomers, namely the E- and Z-isomers. Both doxepin isomers bind to histamine H1 receptor (H1R), ...

The isomers of these bonds can be either Z-shaped or E-shaped. The challenge in fine chemical synthesis is separating the two in order to access the desired compound, Hoveyda said. "It is ...

Binding characteristics of the doxepin E/Z isomers to the histamine H1 receptor revealed by receptor-bound ligand analysis and molecular dynamics study ...