Dynein is a dimeric molecule made up of two copies of six different protein subunits, with motor domains that attach to the microtubule surface via long stalks.

Figure 1: Schematic diagram of a flagellum and dynein arms. To understand the mechanism of ATP-driven force generation during the flagellar bending motion, we reconstructed 3D structures of ...

Cryo-EM uses beams of electrons to construct a 3D image of a molecule with down-to-the-atom detail. Previous studies have used cryo-EM and other imaging methods to construct images of dynein in its ...

Cryo-EM uses beams of electrons to construct a 3D image of a molecule with down-to-the-atom detail. Previous studies have used cryo-EM and other imaging methods to construct images of dynein in its ...

To understand how this essential protein machine works, Reck-Peterson and colleagues decided to study the dynamics of motor movement on the nanoscale by developing protein engineering methods and then ...

Jie Huang, Takeshi Imamura, Jerrold M. Olefsky, Insulin Can Regulate GLUT4 Internalization by Signaling to Rab5 and the Motor Protein Dynein, Proceedings of the National Academy of Sciences of the ...

Science, founded by Thomas A. Edison in 1880 and published by AAAS, today ranks as the world's largest circulation general science journal. Published 51 times a year, Science is renowned for its ...