More information: Martin Miguel Casco-Robles et al, One-step Cre-loxP organism creation by TAx9, Communications Biology (2025 ...

They cloned large fragments of human chromosomes into a mitotically stable human minichromosome using Cre/LoxP-mediated translocation and telomere-directed truncation of the chromosome fragments ...

Mice and newts were applied to the one-step Cre-loxP organism creation technology by TAx9. In this study, the researchers succeeded in synthesizing a Cre-loxP integrated vector by placing a short ...