Rob Lowe got turned down for the role of a lifetime — by his own son John Owen Lowe! When DECIDER caught up with Rob via Zoom ...

Rob Lowe opened up to PEOPLE about his late grandmother’s breast cancer journey and her success in a clinical trial. He’s now raising awareness for clinical trials in her honor.

Almost exactly a year after he was diagnosed with colorectal cancer, WGN-TV reporter Mike Lowe’s cell phone pinged as he drove to work early last week. It was a message from his doctor — the ...

Lowe responded. “There’s only nine years between us and he looks so much better,” Roker chimed in. “Al, you need to get a traveling facelift doctor,” Lowe quipped. “I mean, you got to ...