Neither vector-specific antibody responses nor alterations ... this is the first report to demonstrate that IL-4 can protect against spontaneous diabetes in NOD mice in an Ad-based systemic ...

to jointly examine the efficacy of Amarna’s SVec™ gene delivery vector to develop effective immunotherapies for diabetes mellitus type 1 (DM1) and multiple sclerosis (MS). The collaboration is a joint ...

Type 1 diabetes, a chronic autoimmune disease ... The team engineered an adeno-associated viral (AAV) vector that delivered two proteins — Pdx1 and MafA — to the mouse pancreas.