Detecting presence of the protein αB-crystallin could help predict whether certain breast cancers are likely to spread to the brain. In triple-negative breast cancer (TNBC), tumors commonly ...

Dynamic disulfide exchange in a crystallin protein in the human eye lens promotes cataract-associated aggregation. Journal of Biological Chemistry , 2018; 293 (46): 17997 DOI: 10.1074/jbc.RA118.004551 ...

Background. alphaB-crystallin is a small heat shock protein that has recently been characterized as an oncoprotein correlating with the basal core phenotype and with negative prognostic factors in ...

Crystallin Premium PDC 500 can also be laminated to a substrate of blue Micro and Mini LEDs, providing a color gamut as high as 95%, similar to the performance of a non-cadmium quantum dot film ...

Reference: Rajasekaran et al.: "Human aB-Crystallin Mutation Causes Oxido-Reductive Stress and Protein Aggregation Cardiomyopathy in Mice." Publishing in Cell 130, 427--439, August 10, 2007. DOI ...

Background: Basal-like breast cancers are high grade tumors with poor prognosis, having propensity for brain and lung metastasis (Perou et al. Nature 406:747–52, 2000, Cheang et al. Clin Cancer Res 14 ...

Cataracts are caused by damaged crystallin proteins in the eye lens. These proteins start off soluble and transparent, but they are never replaced and can become mis-folded over time forming ...

Prostate cancer: µ-crystallin (CRYM) protein inhibits tumour growth - diagnostic marker opens up possible target for new forms of treatment. Credit: Medical University of Vienna ...

Other tests showed that alpha-B-crystallin cut production of damaging inflammatory immune chemicals and boosted levels of protective ones. What is more, the protein did not have side effects.

The HE10/97 trial [30] was a randomized phase III trial (ACTRN12611000506998) in patients with high-risk node-negative or intermediate/high-risk node-positive operable breast cancer, comparing ...