A new editorial paper was published in Oncoscience (Volume 10) on November 14, 2023, entitled, "Be mindful of potential pitfalls when using the Cre-LoxP system in cancer research." ...

Cre- loxP recombination allows scientists to excise, insert, or invert specific DNA segments with unprecedented accuracy. 1,2 This works through two key components: a Cre recombinase and loxP sequence ...

All our multiexpression systems (currently MultiBac, MultiMam and MultiColi) rely on in vitro Cre-loxP recombination of Acceptor and Donor plasmids to assemble multiprotein expression vectors. A ...

Dr. Moreno’s lab is part of the Children's Nutrition Research Center which houses laboratories of varied disciplines, a vast array of state-of-the-art equipment, a greenhouse, observation labs and ...

When Cre recombinase (red circle) is introduced, either as a transgene by crossing into a mouse line carrying the targeted gene locus or on a viral vector, the DNA between the loxP sites (red ...