A novel PET imaging approach can effectively quantify a key enzyme associated with brain inflammation, according to research ...

NSAIDs work on a chemical level. They block the effects of special enzymes -- specifically Cox-1 and Cox-2 enzymes. These enzymes play a key role in making prostaglandins. By blocking the Cox ...

It's not completely clear how acetaminophen works, but research suggests that it helps to reduce pain and fevers by inhibiting the COX enzyme. The COX enzymes form prostanoids, which are ...

When investigating NSAID inhibition of COX in vitro some important considerations are the source of the enzyme, the Michaelis constant (K m) of the endogenous substrate arachidonic acid ...

A novel PET imaging approach can effectively quantify a key enzyme associated with brain inflammation, according to research published in the March issue of The Journal of Nuclear Medicine.

Cyclo-oygenase (COX) was the key enzyme that these drugs inhibited. Later, two forms of COX were identified, and it was possible to selectively inhibit each of them. For a general summary overview ...

A novel PET imaging method, using the radiotracer 11C-MC1, successfully quantifies COX-2 enzyme levels in the human brain. This technique opens the door for earlier detection, monitoring of disease ...

A novel PET imaging approach can effectively quantify a key enzyme associated with brain inflammation, according to research ...

Important considerations when investigating NSAID inhibition of COX in vitroare the source of the enzyme, the Michaelis constant (K m)of the endogenous substrate arachidonic acid, the mechanism of ...