The paper S. Kaur et al., “An unmet actin requirement explains the mitotic inhibition of clathrin-mediated endocytosis,” eLife, 3:e00829, 2014. For decades, scientists observed clathrin-mediated ...

The role of the adapter protein PICALM (phosphatidylinositol-binding clathrin assembly protein) in the development of Alzheimer's disease is well documented. Researchers from the German Institute ...

Some steps of membrane transport require the formation of vesicles coated with COPI, COPII or clathrin. The coats probably generate the forces necessary to bend a relatively flat membrane into a ...

In our lab, we focus on clathrin-mediated endocytosis, the predominant route for membrane internalisation in most cells. In addition to its role in endocytosis, the clathrin machinery also forms ...