Ciprofloxacin impairs mitochondrial DNA replication initiation through inhibition of Topoisomerase 2. Nucleic Acids Research , 2018; DOI: 10.1093/nar/gky793 Cite This Page : ...

H-89 treatment inhibited PKA activation by CT but did not protect the cells from apoptosis and growth inhibition. In WEHI-3B/CTRES no significant CT-dependent accumulation of cAMP occurred with ...

Purpose: The effect of omeprazole on the oral bioavailability and urinary exposure of the Depomed formulation of extended-release(ER) ciprofloxacin was studied. Methods: A two-way crossover study ...

Ciprofloxacin 400 mg twice daily IV will achieve the recommended PK-PD goal (AUC 0–24 /MIC ratio >125) in most patients on CVVHDF. Concomitant hepatic and renal impairment results in a prolonged ...

Ciprofloxacin suppressed DNA synthesis of all colon carcinoma cells time- and dose-dependently, whereas the hepatoma cells remained unaffected. Apoptosis reached its maximum between 200 and 500 ...