The chromosome findings in 1084 patients studied ... One (Case 13) was normal each time, and 5 others (Cases 1, 2, 3, 6 and 11) were abnormal on each occasion. The percentage of cells with breaks ...

A chromosomal abnormality occurs when there is an incorrect number of chromosomes, an incorrect amount of DNA within a chromosome, or chromosomes that are structurally flawed. These abnormalities ...

An example of a balanced structural change is the Philadelphia chromosome translocation previously described. In that case, although genetic information was rearranged into an abnormal gene ...

Hassold T, Chiu D . Maternal age-specific rates of numerical chromosome abnormalities with special reference to trisomy. Hum Genet 1985; 70: 11–17. Lin CC, De Braekeleer M, Jamro H . Cytogenetic ...

[44] Combining a limited karyotype with the more objective microarray data will allow for a clearer interpretation for any disease-causing chromosome abnormalities, if any, in the fetus undergoing ...

Microarray analysis identifies more chromosome abnormalities than traditional karyotyping in prenatal testing. Microarrays will also identify findings of unclear clinical significance that should ...