Thanks to the process of chromatin remodeling, this complex can be "opened" so that specific genes are expressed. Various molecules called chromatin remodelers provide the mechanism for modifying ...

So how does the cell know where to uncoil in a process called chromatin remodeling? As previously mentioned, chromatin is remodeled (and thus, nucleosome structure is altered) primarily through ...

ultimately leading to sustained productive chromatin remodeling at these sites. Finally, by systematically comparing across a variety of remodeler mutants implicated in different cancers across ...

More information: Luay M. Almassalha et al, Chromatin conformation, gene transcription, and nucleosome remodeling as an emergent system, Science Advances (2025). DOI: 10.1126/sciadv.adq6652 ...