Each of our cells store their genetic information in the nucleus (genomic DNA) and mitochondria (mitochondrial DNA). A ...

Chen’s discovery of cGAS, short for cyclic guanosine monophosphate-adenosine ... DNA is normally contained in the nucleus and mitochondria, so when it shows up where it doesn’t belong—like outside the ...

But it became increasingly clear that there was also a mechanism driving recognition of microbial DNA within the cytosol (cellular fluid outside the nucleus ... The cGAS-STING pathway begins ...