A recent Cell Reports paper by the Oxenius group (IMB) demonstrates a function of targeted centrosome inheritance during CD8 + T cell division for the generation of memory precursor cells.

For almost a century, our understanding of the tiny structure at the centre of the cell called the centrosome was limited to its ability to organize mitotic spindles and other microtubule arrays.

Various subcellular constituents, including transcripts, native and misfolded proteins, centrosomes and DNA, segregate asymmetrically during cell division into individual daughter cells.

As the centrioles move toward the poles of the cell, they create a region of cytoskeletal production called the centrosome. Be mindful of the vocabulary you introduce to your students. The long ...

These centrosomes, composed of centrioles surrounded by a protein-dense matrix, act as hubs for cell cycle regulators. In organisms like yeast, spindle pole bodies (SPBs) function similarly but ...

TEDC1 and TEDC2, functions in generating centriolar triplet microtubules, and that this is crucial for the proper formation of centriolar subdomains and the stability of centrioles throughout the cell ...

During synapse formation, these granules coalesce around the CTL centrosome, which reorients to a position just beneath the cell-cell contact. Concomitantly, filamentous actin at the interface is ...