Analysis of actin-based cellular motility illustrates how the reductionist strategy can be used to decipher a complex mechanism. So far, many of the key proteins have been identified and shown to ...

Rapamycin, an inhibitor of the mammalian target of rapamycin (mTOR), inhibits tumor cell motility. However, the underlying mechanism is poorly understood. Here, we show that rapamycin inhibited ...

Motility – albeit on a cellular spatial scale -- is necessary for wound healing, clotting, fetal development, nerve connections, and the immune response, among other functions.

Many cellular functions rely on that movement, including cell differentiation, wound repair, embryonic development, angiogenesis, and tumor metastasis. In this Teach Me in 10, Hilary Sherman, Senior ...

The Key To Cell Motility Date: July 2, 2004 Source: Scripps Research Institute Summary: Scientists at The Scripps Research Institute have described the regulatory mechanism of an important human ...

A key cell-movement protein called IRSp53, as described by researchers, is regulated in a resting and active state, and in a new study, they address what this means for cancer-cell metastasis. "We ...

Cell motility mystery cracked—the protein that re-charges the cell's motility machinery revealed. Your friend's email. Your email. I would like to subscribe to Science X Newsletter.

Liquid-liquid phase separation (LLPS) has emerged as a major organizing principle in cells. Recent work showed that multiple components of integrin-mediated focal adhesions, including p130Cas can form ...

A 96-well cell motility assay platform from Platypus Technologies utilizes cell-seeding stoppers to create a detection zone for visualizing cell migration and invasion as the assay progresses.

Starz-Gaiano's work on cell motility during egg development started at the Johns Hopkins University School of Medicine with Denise Montell, director of the Center for Cell Dynamics.

Cellular motility refers to the cell's movement in response to chemical signals. Many cellular functions rely on that movement, including cell differentiation, wound repair, embryonic development, ...