In architecture, the word niche refers to a recess, and in ecology it refers to a habitat where an organism can reside and reproduce; in French, it refers to a dog-house. So, the grand position of ...

If commonalities are found, then the microenvironment can be perturbed to learn which aspects, if any, affect stem cell behaviour. Showing that a niche is present requires ultimately that stem ...

a major component of the hematopoietic stem cell niche, demonstrated severe myelofibrosis and defects in the production of blood cells. Runx1 and Runx2 may act as potential targets in the ...

The local stem cell environment (niche) is vital for stem cell maintenance and function in many tissues, and tenascin C in particular has been shown to play an important role within stem cell niches ...

New formation of neurons from stem cell niche disrupted after stroke Date: October 24, 2024 Source: University of Freiburg Summary: Researchers studied what happens immediately after a stroke in ...

More information: Bahar Degirmenci et al, GLI1-expressing mesenchymal cells form the essential Wnt-secreting niche for colon stem cells, Nature (2018). DOI: 10.1038/s41586-018-0190-3 Journal ...

Organoids can be derived from stem cells or tissue-specific progenitor cells. A stem cell niche is the specific microenvironment that regulates the stem cell behaviors. Many researchers try to ...

Now, researchers in Japan have shed new insight into the dynamics of the neural stem cell niche, the home of stem cells in the brain. In a new study published in Inflammation and Regeneration ...

but expressed the satellite cell marker paired box 7 (Pax7). “What he found was that, in the niche created in the organoid, satellite cells that were not there to start with appeared. In other words, ...

In healthy rodent brains, newborn neurons are constantly generated in the stem cell niche, known as the subventricular zone (SVZ). These cells might help to repair a brain that has been damaged by ...