New understanding of B cell mutation strategies could have implications for vaccines
A vaccine's ability to generate long-lasting, high-affinity antibodies hinges on a delicate balance. Upon exposure to a ...
Malicious jumping genes meet their match: Study reveals cell's adaptive piRNA defenses
Adverse genetic mutations can cause harm and are due to various circumstances. "Jumping genes" are one cause of mutations, ...
Scientists uncover hints of a potential new cause of stomach cancer
For the first time, scientists have systematically analyzed somatic mutations in stomach lining tissue to unpick mutational ...
Science Daily19h
New mechanism behind adaptive immunity revealed: It could impact how we design vaccines
New imaging reveals a built-in safeguard that allows B cell populations to rapidly expand in germinal centers without introducing deleterious mutations.
The New Cancer Theory That Could Change Everything We Know
In a recent essay, scientists challenge the prevailing genetic-focused model of cancer, advocating for a shift towards more ...
Live Science on MSN7d
POLG diseases: Rare genetic conditions that starve cells of energy and afflicted the late Prince of Luxembourg
POLG-related diseases disrupt the function of the mitochondria, or "powerhouses" of the cell — starving them of energy.
Multiple Sclerosis News Today9d
Cells in MS lesions found to acquire mutations faster than healthy cells
Neurons collected from brain lesions in MS patients were found to accumulate new genetic mutations faster than healthy nerve ...
University of California4h
Breathing new life: Working toward an inhalable gene therapy for cystic fibrosis
Although cystic fibrosis is a single gene mutation, there are more than 1,000 different ways the CFTR gene can mutate in ...
BioTechniques3d
Regular blood donation could promote beneficial genetic changes
Researchers have discovered genetic mutations in frequent blood donors that may promote the production of healthy cells ...
GEN - Genetic Engineering and Biotechnology News21h
Gene Therapy Tested in Mice Offers New Hope for People with Dravet Syndrome
By replacing the defective gene associated with Dravet syndrome in mice, scientists successfully alleviated symptoms without ...
Cells 'speed date' to find their neighbors when forming tissues
In developing hearts, cells shuffle around, bumping into each other to find their place, and the stakes are high: pairing ...
Gradalis Announces Development of Clinically Relevant Exome Sequencing Bioinformatics Pipeline to Determine Clonal Tumor Mutation Burden
Optimal therapeutic targeting of cancer involves clonal signals which are expressed within all cancer cellsGradalis applies a novel clinically relevant approach to determine clonal tumor mutation ...