Researchers at the Center for Embryology and Healthy Development (CRESCO) aim to find out why so many early embryos fail in ...
"These cells co-develop together, just like they would in an actual embryo, and establish that history of being neighbors," ...
Scientists have found a way to study early embryonic development without real embryos. Using CRISPR, they programmed stem cells to self-organize into structures mimicking early embryos. The cells show ...
For several years, researchers studied human embryonic stem cells (ESCs) to understand the unique features of these pluripotent cells, but on their own, they poorly resembled the complex structures ...
A research team showed that, contrary to current models, one early embryonic cell dominates lineages that will become the fetus. Shelby is an Assistant Editor for The Scientist. She earned her PhD ...
Scientists at the University of California, Santa Cruz (UCSC), used CRISPR to engineer cellular models of embryos that mimic what happens in the first few days after reproductive cells meet.
The fusion of sperm and egg gametes during human fertilization establishes a diploid zygote and initiates a series of cell divisions that result in a multicellular embryo. The blastocyst stage is ...
If cells are removed from the embryo they will differentiate into any cell type. These are called embryonic stem cells. Some stem cells remain in the bodies of adults as adult stem cells.
Pluripotent stem cells are cells that have the capacity to self-renew by dividing and to develop into the three primary germ cell layers of the early embryo and therefore into all cells of the ...
To more easily detect mRNA trafficking from one cell to another, the researchers employed a coculture experimental system. Simply put, they cultured mouse embryonic stem cells (mESCs) alongside ...
To understand how genes are turned on and off to make different cell types, you have to figure out how the DNA is folded — and which genes and enhancers are paired together. In a mouse or human embryo ...