Under physiological conditions, the antioxidant functions of p53 are mediated by p53R2, which maintains increased catalase activity and thereby protects against endogenous ROS. After genotoxic ...

Cells can defend themselves with detoxifying enzymes like catalase and superoxide dismutase that break down ROS. The balance between production of ROS and their destruction by antioxidant enzymes ...

intracellular ROS play no role for apoptosis induction in glutathione-depleted transformed fibroblasts initially, since a high level of intracellular catalase scavenges intracellular hydrogen ...

and polyphenols directly scavenge ROS or regenerate oxidized enzymatic antioxidants. Enzymatic antioxidants-including superoxide dismutase (SOD), catalase (CAT), glutathione peroxidase (GPx ...

they revealed the catalytic role of reactive oxygen species (ROS) superoxide (O 2 •-) in the heme-catalase-mediated synthesis of ergot alkaloids (EAs), a group of medicinal natural products for ...

The new study shows that tumor cells with low levels of catalase enzyme activity ... a so-called reactive oxygen species that can damage tissue and DNA. The study also shows that tumor cells ...

catalase, and thioredoxin. The fact that cancer cells largely driven by RAS and Myc are among the most difficult of cancers to treat could be due to their high levels of ROS-destroying ...

Catalase is an antioxidant enzyme responsible ... hydrogen peroxide can be converted into more toxic reactive oxygen species, which in turn cause oxidative damage to DNA, proteins, and lipids ...

In a perfect world, and healthy body, the peroxide you create will rapidly turn into water and oxygen, with the help of an enzyme called catalase (you make that too). It's the oxygen coming off ...