AbbVie is on board with the idea. The Big Pharma will pay up to $2.1 billion in cash at closing to acquire Capstan. In return ...

The FDA has eliminated REMS for BCMA- and CD19-directed CAR T-cell therapies, improving access and reducing provider burden. Hospitals no longer need special certification or immediate access to ...

The acquisition will expand AbbVie's exploration of in vivo CAR-T therapy, an ambitious approach that could sidestep some of the difficulties presented by current cell treatments.

Researchers use targeted lipid nanoparticles loaded with mRNA to reprogram T cells to fight autoimmune diseases ...

The culture conditions used at Galapagos in the Cocoon® promote the outgrowth of CAR T-cells that have a less differentiated, naïve, and stem-like memory phenotype that show greater expansion ...

Patients with systemic lupus erythematosus who received autologous chimeric antigen receptor T-cell therapy enjoyed potent ...

A next-generation, anti-CD19 enhanced (or "armored") CAR T-cell product showed promising efficacy and safety in a phase I trial of lymphoma patients who had previously failed anti-CD19 CAR T-cell ...

Researchers have discovered that some CAR-T cells engineered to fight cancer and other conditions carry the memory of past encounters with bacteria, viruses and other antigens within them, a ...

FDA updates CAR T-cell therapy labels for liso-cel and ide-cel, easing monitoring requirements and expanding access for ...

Step Five: Receiving your CAR T-cell therapy. The final step of the process is the infusion of the newly created CAR T cells. But first, you’ll have a final evaluation to be sure you’re ready.

Chimeric antigen receptor (CAR) T-cell therapy has been an exciting area of development for autoimmune disease treatment. Previous reports had not mentioned any particular constellation of adverse ...

Renier Brentjens, a CAR T-cell pioneer, views armored CAR T-cells as a promising avenue for treating solid tumors and predicts that a treatment could be approved in the next 5-10 years.