In the past 5–10 years there has been a growing trend for substituting conventional 5-fluorouracil with the oral prodrug of 5-fluorouracil, capecitabine, in chemotherapy regimens. This regimen ...

Each pill contains one of the company’s sensors and can record when it’s ingested—a trick that Greeno and his collaborators are hoping will help doctors ensure that patients are taking their ...

Herrmann et al. compared the safety and efficacy of gemcitabine plus capecitabine (GemCap) with that of gemcitabine monotherapy in patients with pancreatic cancer. This phase III trial included ...

During the first cycle of capecitabine development, three concomitant drugs were found to affect 5-FU clearance. [5] Paracetamol and morphine increased 5-FU clearance by 26% and 41%, respectively ...