Calico Cats usually have beautiful and unique tri-color patterns. They are almost exclusively female cats, with exceptions ...

Owner Mariacarla Caruso of Italy told Newsweek about the TikTok video that has brought in over 26 million views.

X inactivation only occurs in cells with multiple X chromosomes, which explains why almost all calico cats are female. X inactivation exists in two different forms: random and imprinted.

Conversely, calico or tortoiseshell cats are usually female – the female’s extra X chromosome allows the possibility of her receiving both a black and orange gene. 1. https://be.chewy.com ...