CYP17A1 serves two distinct enzymatic functions in androgen synthesis. The first of these functions is as a 17α-hydroxylase, which is also required for cortisol synthesis.

The CYP17A1 inhibitors market is projected to attain USD 1,350 million by 2025, expanding at a robust CAGR of 8.5% between 2025 and 2032, supported by strong pipeline activity, expanded indications, ...

The inhibition of CYP17A1 by ODM-204 was studied in vitro by using human and rat testicular microsomes and a human adrenal cortex cell line, and in vivo in male rats coadministered with luteinizing ...

VT-464 is a novel, non-steroidal, small molecule CYP17A1 inhibitor with selectivity for the lyase activity of this dual enzyme. The objective of this study was to evaluate the anti-cancer activity of ...

We evaluated whether variation in genes related to estrogen metabolism (COMT, CYP1A1, CYP1B1, CYP17A1, CYP19A1, ESR1, GSTM1, GSTP1, GSTT1, HSD17B1, SULT1A1, and UGT1A1) contributes to breast cancer ...

The CYP17A1 inhibitors market is projected to attain USD 1,350 million by 2025, expanding at a robust CAGR of 8.5% between 2025 and 2032, supported by strong pipeline activity, expanded ...