Another form of subunit vaccine is the vectored one: the gene for the CMV antigen is expressed in a non-replicating vector. The vectors used for these vaccines are canary-pox, adenovirus ...

New preclinical data demonstrates that CMV antigens identified with Evaxion’s AI-Immunology™ platform trigger targeted immune responses Results also showcase the successful design of a ...

In the case of CMV disease high-dose immunoglobulin was given as well. In the allogeneic setting 16 out of 74 (22%) patients developed a positive PCR. Seven episodes of a positive pp65 antigen ...

The decision to use pre-emptive therapy was based entirely on a positive antigenemia test (⩾3/50 000 antigen-positive cells), independent of the quantity of CMV DNA detected. Intravenous ...

Preconceptional immunity against cytomegalovirus (CMV) provides only partial protection against intrauterine transmission of the virus. Whether congenital CMV infection in the offspring of women ...

Cytomegalovirus (CMV) infection can convert a harmless, inhaled protein antigen into an allergen, according to a study published March 7 in the open-access journal PLOS Pathogens by Rafaela ...

The primary end point was all-cause prophylaxis failure, defined as discontinuation of the study drug because of CMV antigen or DNA detection, end-organ disease, or any other cause. Patients ...

ITI’s dendritic cell vaccine is designed to target the pp65 viral antigen of Cytomegalovirus (CMV) that is expressed in GBM, but not in normal brain cells. In the ATTAC studies, the GBM patients ...

The data demonstrates that the antigens identified with Evaxion’s AI-Immunology™ platform effectively trigger targeted immune responses, including induction of both CMV reactive B and T cells.

Results also showcase the successful design of a proprietary prefusion glycoprotein B (gB) antigen with ability to neutralize the virus About 1 in 200 babies is born with congenital CMV infection ...

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