a gene called CDKN2B, which regulates cell division; a gene called APOE, which is linked with Alzheimer's disease; and a gene called SH2B3, which was previously found to extend life in fruit flies.

The complexity of gene expression includes alternative splicing mechanisms, 1 alternative promoter–enhancer usage, 2 intronic gene expression, 3 expression of inhibiting RNAs, 4 and effects of ...

M.P.H., Sc.D. "This newly found link in African-Americans was not only protective instead of harmful but was also found at a precise location on gene CDKN2B, a gene close to the single base pair ...

For example, some mutations in the CDKAL1 gene are associated with reduced insulin production, which increases blood glucose levels. CDKN2A and CDKN2B genes: CDKN2A/2B genes (cyclin-dependent ...

The patients were enrolled in the biomarker-enriched, Cohort 8 of the proof of concept study and were preselected for CDKN2A and/or CDKN2B abnormalities. “We are encouraged by the interim data ...

gene and the low-density lipoprotein receptor (LDLR), Nicotinic Acetylcholine Receptor 3/5 (CHRNA 3/5), Lipoprotein A (LPA), and Cyclin-dependent Kinase Inhibitors 2B Antisense RNA 1 (CDKN2B-AS1 ...