News

KTLA1mon
Mozart Therapeutics Presents Preclinical Data Showing Restoration of CD8 Treg Functionality in Type 1 Diabetes and Early Data from their Targeted IL-15 Program at Immunology ...
A second presentation illustrates pre-clinical work showing that a targeted IL-15 mutein promotes the selective expansion, activation, and cytolytic functions of CD8 Treg. Targeted IL-15-mediated ...
The Victoria Advocate7mon
Mozart Therapeutics Announces Publication of MTX-101 Preclinical Data Demonstrating Modulation of Regulatory CD8 T Cell Network to Restore Immune Homeostasis
Preclinical Data Show MTX-101 Selectively Binds CD8 Treg, Restores Elimination of Autoreactive Cells, and Confirms Therapeutic Potential in Multiple Autoimmune Disease Models Phase 1 Clinical ...
GEN1y
Checkpoint Therapy Could Be Enhanced by Cutting CD8+ T Cell/Treg Crosstalk
Indeed, the scientists have found that interrupting CD8 +-to-Treg signaling before PD-1 immunotherapy “improves control over immunogenic melanoma.” “[We] show that PD-1 blockade increases ...
BioWorld1y
Mozart Therapeutics’ bispecific CD8 Treg modulator does not increase unwanted immune cell activation, pro-inflammatory cytokines
Mozart Therapeutics Inc. has reported preclinical pharmacologic and tolerability data for MTX-101, a bispecific CD8 regulatory T-cell (Treg) modulator targeting inhibitory KIR2DL(1/2/3) and CD8 ...
KRON4 News1mon
Mozart Therapeutics Presents Preclinical Data Showing Restoration of CD8 Treg Functionality in Type 1 Diabetes and Early Data from their Targeted IL-15 Program at Immunology ...
Presentations underscore Mozart's commitment to advancing scientific understanding of the CD8 Treg network and developing therapies that restore endogenous CD8 Treg mechanisms for the treatment of ...