In mice infected with lymphocytic choriomeningitis virus (LCMV), Ahmed found PD-1 upregulated in functionally-impaired CD8 T cells. The team then showed that preventing PD-1 activation by blocking its ...

Recently, the research team led by Professor Zhang Zhongtao and Professor Yao Hongwei from the General Surgery Center at ...

gondii are unstable. Although the host contributes to this instability via expression of down-regulatory proteins (PD-1) on the surface of the CD8 T cells (Figure 2), whether and how the parasite ...

CD8 T cells lacking Tet1/3 preferentially differentiate into short-lived effector and effector memory cells following acute ...

CD8 + T cells that normally kill cancer cells ... of three markers involved with antigen presentation, MHCI, MHCII, and PD-L1, and their release of two markers of immunogenic cell death, ATP ...