Figure 1: MAIT cells are located in the gut lamina propria of both humans and mice. Figure 3: MR1 is the restricting MHC molecule for MAIT cells. Figure 4: MAIT cells are absent in germ-free mice.

What Is the CD4:CD8 Ratio Test Used For? CD4 and CD8 are two types of white blood cells in your blood. White blood cells help your body fight infections. If you have HIV infection, your doctor may ...

These cDCs present brain-derived antigens to T cells sitting in the cervical lymph nodes. In ApoE4 carriers, CD8+ T cells more easily cross from the blood into the brain. In tauopathy mice, antigens ...

They found associations between CD8+ T cell subtypes, characterized three distinct exhausted T cell subtypes, and revealed diverse clonal and transcriptomic patterns in autoimmune and immune ...

Within the immune system, CD8 + T cells are the main defensive adaptive immune cells protecting against tumor cells. However, the mechanism by which aging impairs the antitumor response of CD8 + T ...

A variant form of LGL leukemia involves a specific T cell called CD8+. CD8+ T cells are T cells that carry the co-receptor CD8. A co-receptor is a surface protein that makes antigen receptors more ...

Researchers from the University of Pittsburgh Center for Vaccine Research report that innate CD8+ lymphocytes are essential for curbing tuberculosis (TB) the disease. They also discovered that ...

Study uncovers a pathogenic subset of memory T-cells that promote tissue inflammation and highlights a potential target for treating nasal polyps and other inflammatory airway diseases. Study ...

The mouse-based study, published in the Journal of Experimental Medicine, uncovered a new way to enhance stem cell-like memory CD8+ T cells following vaccination, pointing to a future where more ...

A study in the journal Science Immunology now shows how two subsets of one type of immune cell -- the CD8 T cell -- develop to provide either short-term or long-term immune protection. The study ...