In a study of the immune systems of mice, scientists at Johns Hopkins Medicine say they have found a new role for a protein, QRICH1, which could become a target for drugs to dial up or down the ...

Ten years of substantial work by Université de Montréal immunologist Nathalie Labrecque's team at the Montreal Clinical ...

Chinese scientists have revealed a hidden metabolic partnership between breast cancer cells and immune cells that drives aggressive tumor behavior and resistance to immunotherapies. The study sheds ...

CD8 T cells lacking Tet1/3 preferentially differentiate into short-lived effector and effector memory cells following acute ...

Researchers have revealed a hidden metabolic partnership between breast cancer cells and immune cells that drives aggressive tumor behavior.

Traditional vaccines work by stimulating the immune system, but their effectiveness is often limited by how well they can ...

A groundbreaking study published in Research (2025, DOI: 10.34133/research.0545) has elucidated the molecular mechanisms by which protein phosphatase 2A (PP2A) regulates CD8+ T cell-mediated immune ...

Once acquired infection persists for life requiring continuous life long cellular immunity (CD8 memory T cell and IFNγ dependent) for host survival. Development of this response relies on both ...

A phase 3 trial of nemvaleukin alfa in with Keytruda for patients with platinum-resistant ovarian cancer will not continue on ...

Tertiary lymphoid structures (TLS) are increasingly recognized to have roles in cancer. Within tumor microenvironments (TME), TLS can arise as ectopic lymphoid organs containing aggregates of ...