Stem cell factor (SCF) and its receptor c-kit take part in the regulation of developmental processes of mast cells, hematopoietic stem cells, and melanocytes, as well as in the growth control of ...

c-Kit (CD117), a type III receptor tyrosine kinase (RTK), is involved in intracellular signaling. c-Kit and its ligand stem cell factor (SCF) are essential for embryonic development and the ...

ALY-301 is a first-in-class bispecific antibody targeting c-Kit and CD-203c with mast cell selectivity Designed to enable safe dosing in chronic conditions and deliver clinical proof-of concept in a ...