Want to now add a second connection to one of the carbons at either end of your bridgehead to form an organic double bond known as an olefin? Bredt would have said sorry, you're out of luck.

UCLA chemists believe it’s time to rewrite the textbooks as they figured out how to violate Bredt’s rule, which will help chemists discover new medicines. In 1924, Bredt’s rule was more or ...