Reference: Choi S, Whitman MA, Shimpi AA, et al. Bone-matrix mineralization dampens integrin-mediated mechanosignalling and metastatic progression in breast cancer. Nat Biomed Eng. 2023. doi: ...

The 7 key factors beyond calcium for optimal bone health. Research from leading institutions worldwide has identified several critical factors that influence bone formation, maintenance, and loss ...

However, the bone matrix is composed of hundreds of proteins that are poorly understood and may play a major regulatory role in bone regeneration and osteoporosis. "Our project has identified 255 ...

Mineralization of bone matrix regulates tumor cell growth. Cornell University. Journal Nature Biomedical Engineering DOI 10.1038/s41551-023-01077-3 ...

The research, conducted with the aim of improving early management and surgical outcomes for bone infections, focused on modifying demineralized bone matrix (DBM), a naturally derived material ...

In this matrix, made of a soft hydrogel, the cells (osteoblasts) that form bone can settle, multiply and connect with each other and their offshoots to form a three-dimensional network.

Journal Article Histological Remodelling of Demineralised Bone Matrix Allograft in Posterolateral Fusion of the Spine; 2001 /s/viewarticle/804316 ...

Bone-matrix mineralization dampens integrin-mediated mechanosignalling and metastatic progression in breast cancer. Nature Biomedical Engineering , 2023; DOI: 10.1038/s41551-023-01077-3 Cite This ...

Tumor cells are known to be fickle sleeper agents, often lying dormant in distant tissues for years before reactivating and forming metastasis. Numerous factors have been studied to understand why the ...