Mapping an antibody’s epitope, where it binds a target, can now be done in three dimensions, which optimizes the selection of application-specific antibodies.

A multi-institutional team of investigators have developed a catalog of transcription factor binding sites that regulate gene expression across the genome, according to a recent study published in ...

Traditional methods for determining binding sites and affinities typically require the purification of recombinant proteins, which can be both time-consuming and labor-intensive. In addition ...

A typical footprinting experiment involves radioactive labeling of the DNA region of interest—usually a larger chunk of DNA suspected to contain one or more transcription factor binding sites.

Among the highest rating patterns most have matches to substrings in known yeast transcription factor binding sites. Moreover, several of them are known to be relevant for the expression of the ...

The 3D visualization provides scientists with a clear and detailed representation of the antibody-binding sites, enabling improved speed and precision of their antibody selection. In addition to ...